A MILD AND CONVENIENT ONE-POT SYNTHESIS OF 4,6-DIARYL-3-AMINOISOXAZOLO[3,4-b]PYRIDINES

摘要

-We have developed a convenient method for the synthesis of a series of new 4,6-diaryl-3-aminoisoxazolo[3,4-b]pyridines through one-pot reaction starting from the easily available chalcones, malononitrile, and hydroxylamine. This class of compounds might have potential pharmacological activities in medicinal chemistry.