RUMPHELLOLIDE H, A NEW NATURAL CARYOPHYLLANE FROM THE GORGONIAN RUMPHELLA ANTIPATHIES

摘要

A new natural caryophyllane-type sesquiterpenoid, rumphellolide H (1), which possesses a tetrahydropyran moiety in structure, was isolated from the gorgonian coral Rumphella antipathies. The structure of 1 was established by spectral data analysis and this metabolite showed moderate inhibitory effects on elastase release by human neutrophils.