3',4'-DIHYDRONORSTEPHASUBINE, A NEW BISBENZYLISO-QUINOLINE FROM THE BARK OF ALSEODAPHNE CORNERI

摘要

A new bisbenzylisoquinoline, 3',4'-dihydronorstephasubine (1) together with two known alkaloids, norstephasubine (2) and gyrolidine (3) were isolated from the stem bark of Alseodaphne corneri (Lauraceae). The ~(13)C-NMR data for norstephasubine (2) and gyrolidine (3) were also reported. Structural elucidation of 1 was performed by spectral methods such as 1D-and 2D-NMR, IR, UV, and HRMS. 3',4'-Dihydronorstephasubine (1) and gyrolidine (3) showed moderate vasorelaxant effect on rat aorta.