Synthesis of bowl-shaped chiral homotriazacalixarenes: chiral transmission from the point chirality of the bridge to the cyclophane moiety

摘要

Bowl-shaped chiral homotriazacalixarenes were prepared by the cyclization reactions of chiral triamines with three equimolar amounts of bis(chloromethy)phenols or bis(chloromethyl)-phenol-formaldehyde dimers in moderate yields. The structural analysis of the macrocycles by the NMR and CD spectra imply the existence of the chiral transmission from the point chirality of the cysteine bridge to the cyclophane moiety.