NOVEL RADICAL CYCLIZATION METHOD ACCOMPANIED BY ELIMINATION OF HYDRAZYL RADICAL

摘要

The potential of hydrazine group as the new radical leaving group was studied. Radical cyclization of (E)-1,1-dialkyl-2-(1-alkyloct-2-en-7-ynyl)hydrazines with n-Bu3SnH/AIBN, followed by protodestannylation, gave 1-alkenyl-2-methylenecyclopentanes, which arose by 5-exo cyclization and subsequent β-elimination of hydrazyl radical.