A NON-CATALYST METHOD FOR THE SYNTHESIS OF BIS-4-ARYL-3, 4-DIHYDROPYRIMIDONES (THIONES) UNDER SOLVENT-FREE CONDITIONS

摘要

Three component coupling of an aromatic dialdehyde, a β-keto ester or p-diketone and urea or thiourea (1:2.2:2.5 mol ratios) in one-pot under solvent-free conditions without any catalyst produced the bis-dihydropyrimidones (thiones) in a microwave oven. This is therefore a "green" synthesis of the title compounds under the said conditions.