NEW DEVELOPMENTS IN THE SYNTHESIS OF SACCHARIN RELATED FIVE- AND SIX-MEMBERED BENZOSULTAMS

摘要

Recent developments in the novel synthesis of saccharin related five-and six-membered benzosultams are reviewed. The sulfonamide unit has found many applications in medicinal chemistrty. It has been incorporated in a still growing number of biologically active compounds, exhibiting antibacterial, anti-carbonic anhydrase, diuretic, hypoglycemic, antithyroid, antiviral and anticancer activity among others.