STUDIES WITH 3-OXOALKANONITRILES: SYNTHESIS AND REACTIVITY OF 3-OXO-3-(1-METHYLINDOLOYL)PROPANENITRILE

摘要

N-Methylindole was acylated at C-3 with cyanoacetic acid and acetic anhydride to yield 3-cyanoacetyl-1-methylindole which could be utilized for synthesis of a diversity of indole derivatives with heterocyclic substituent.