EREMOPHILANE DERIVATIVES FROM PITTOCAULON PRAECOX

摘要

Five new compounds; two eremophilane glucosides (1, 2) and three eremophilanolides (3, 11, 12), together with several known compounds were isolated from Pittocaulon praecox. Their structures were elucidated by spectroscopic methods. The anti-inflammatory activity of extracts and main isolated metabolites was evaluated on 2-O-tetradecanoylphorbol-13-acetate (TP A) induced model of acute inflammation.