TRISUBSTITUTED DOUBLE BOND IN THE CYCLOOCTENE RING.PREPARATION USING THE RCM REACTION

摘要

Cyclization to eight-membered rings with a trisubstituted double bond was attempted using ring closing metathesis (RCM) reactions. Although simple substrates were not good candidates, the triene with a proper configuration cyclized to the cyclooctene with a tri-cycle (5-8-6 membered) in moderate yield. The formation of one-carbon smaller rings was also observed.