ASYMMETRIC OXIDATION OF CYCLIC SULFIDES CATALYZED BY AN ALUMINUM(SALALEN) COMPLEX AS THE CATALYST

摘要

We report a catalytic asymmetric oxidation of cyclic sulfides that uses a combination of aluminum(salalen) complex 1 as the catalyst and aqueous hydrogen peroxide as the oxidant. Oxidations of six-membered cyclic sulfides, thiochroman-4-ones, furnish the corresponding sulfoxides in high yield with high enantioselectivity. Five-membered 2,3-dihydrobenzo[b]thiophene and seven-membered dibenzo[b,e]thiepin-11(6H)-one are also good substrates for the aluminum-catalyzed system.