SYNTHESIS OF ARTEKEISKEANIN A:A NEW COUMARIN MONOTERPENE ETHER FROM ARTEMISIA KEISKEANA

摘要

The first total syntheses of artekeiskeanin A,a natural coumarin monoterpene ether from Artemisia keiskeana,and 7-geranyloxy-6-methoxycoumarin,a coumarin monoterpene ether with antifungal and antitumor properties,are reported.Key step in the synthesis of artekeiskeanin A is the stereoselective oxidation of the geranyloxy side chain of 7-geranyloxy-6-methoxycoumarin under microwave irradiation.