A NOVEL TWO STEP SYNTHESIS OF 3,4-DIHYDRO-4-OXO-5H-PYRANO [2,3-d] PYRIMIDINES

摘要

A novel two step synthesis of 5,7-diaryl-3,4-dihydro-4-oxo-5H-pyrano[2,3-d]pyrimidines has been reported based on condensation of 2-thiobarbiturates with chalcones followed by reductive desulfurization of 5,7-diaryl-l,2,3,4-tetrahydro-4-oxo-2-thioxo-5H-pyrano[2,3-d]pyrimidines with nickel boride.