A FACILE AND EFFICIENT SYNTHESIS OF MONO- AND BIS-FUNCTIONALIZED meso-SUBSTTTUTED PORPHYRINS VIA PALLADIUM-CATALYZED NEGISHI CROSS-COUPLING

摘要

A series of mono- and bis-functionalized mew-substituted porphyrins bearing chemically reactive functional groups such as -COOR, -Cl, and -CN in the alkyl substituents at the meso positions were efficiently synthesized by the reactions of meso-brominated precursors with alkylzinc reagents via palladium-catalyzed Negishi cross-coupling.