STRAIGHTFORWARD ASYMMETRIC TOTAL SYNTHESIS OF (+)-EVODIAMINE, A MAJOR INDOLE ALKALOID IN HERBAL MEDICINE 'Wu Zhu Yu'

摘要

The concise asymmetric total synthesis of evodiamine, an indole alkaloid in Evodia Fructus, was achieved by employing Noyori's ruthenium(II)-catalyzed asymmetric transfer hydrogenation.