SYNTHESIS OF CHIRAL #alpha#-ACETOXY-N-ACETYLAMIDES FROM CHIRAL PYRIMIDYLALKANOLS BY THE OXIDATIVE CLEAVAGE OF PYRIMIDINE RING

摘要

Acetates of chiral 5-pyrimidylalkanols are transformed into chiral #alpha#-acetoxy-N-acethlamides and #alpha#-acetowyamides without racemization in high total yields by the oxidative cleavage of pyrimidine ring using ruthenium tetroxide.