SUBSTITUENT EFFECTS ON THE RATE OF ACID-CATALYSED EPIMERIZATION OF INDOLO[2,3-a]QUINOLIZIDINES

摘要

10-Substituted indolo[2,3-a] quinolizidine derivatives were prepared to study the effect of substituents on the epimerization rate.Under the conditions employed,electron withdrawing substituents hindered epimerization and electron donating substituents accelerated it.