ISOLATION OF ALKAMIDES WITH DEATH RECEPTOR-ENHANCING ACTIVITIES FROM PIPER CHABA

Tahmina Hogue; Toume Kazufumi; Arai Midori A.; Sadhu Samir K.; Ahmed Firoj; Ishibashi Masami

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ISOLATION OF ALKAMIDES WITH DEATH RECEPTOR-ENHANCING ACTIVITIES FROM PIPER CHABA

机译：从派珀·查巴分离具有死亡受体增强活性的烷基酰胺

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In the screening program for natural bioactive compounds that enhance the expression of death receptor 5 (DR5), activity-guided fractionation of the Piper chaba (Piperaceae) root MeOH extract led to the isolation of four alkamides (1-4). Compounds 1, 3, and 4 enhanced DR5 promoter activity while pellitorine (3) exhibited TRAIL-resistance-overcoming activity.

机译：在增强死亡受体5（DR5）表达的天然生物活性化合物的筛选程序中，对胡椒（Piper chaba（Piperaceae））根MeOH提取物进行活性指导的分馏导致分离出四种烷酰胺（1-4）。化合物1、3和4增强了DR5启动子的活性，而拼花碱（3）具有克服TRAIL的活性。

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《Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry 》 |2015年第2期| 共6页
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Tahmina Hogue; Toume Kazufumi; Arai Midori A.; Sadhu Samir K.; Ahmed Firoj; Ishibashi Masami;
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正文语种 eng
中图分类化学 ;
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1. ISOLATION OF ALKAMIDES WITH DEATH RECEPTOR-ENHANCING ACTIVITIES FROM PIPER CHABA [J] . Tahmina Hogue, Toume Kazufumi, Arai Midori A., Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry . 2015 ,第2期

机译：从派珀·查巴分离具有死亡受体增强活性的烷基酰胺
2. Protective effects of amide constituents from the fruit of Piper chaba on D-galactosamine/TNF-alpha-induced cell death in mouse hepatocytes. [J] . Matsuda H, Ninomiya K, Morikawa T, Bioorganic and Medicinal Chemistry Letters . 2008 ,第6期

机译：墨西哥胡椒（Piper chaba）果实中的酰胺成分对D-半乳糖胺/TNF-α诱导的小鼠肝细胞死亡的保护作用。
3. Protective effects of amide constituents from the fruit of Piper chaba on D-galactosamine/TNF-alpha-induced cell death in mouse hepatocytes. [J] . Matsuda H, Ninomiya K, Morikawa T, Bioorganic and Medicinal Chemistry Letters . 2008 ,第6期

机译：墨西哥胡椒（Piper chaba）果实中的酰胺成分对D-半乳糖胺/TNF-α诱导的小鼠肝细胞死亡的保护作用。
4. Antioxidant Activities of Chaba Maple (Hibiscus acetosella) Flower Extract [C] . Suradwadee Thungmungmee, Nakuntwalai Wisidsri, Warachate Khobjai Uttaradit Rajabhat University International Conference on Science and Technology . 2019

机译：Chaba Maple（芙蓉丙酮肉）花提取物的抗氧化活性
5. Synergistic activity of the monolignol dillapiol and variation of its production in two plants, Anethum graveolens and Piper aduncum. [D] . Belzile, Anne-Sophie. 1998

机译：单木香醇地那普利的协同活性及其在两种植物（Anethumgravolens和Piper aduncum）中的产量变化。
6. Anti-Inflammatory Analgesic and Antipyretic Activities of the Ethanol Extract of Piper interruptum Opiz. and Piper chaba Linn. [O] . Seewaboon Sireeratawong, Arunporn Itharat, Nusiri Lerdvuthisopon, 2012

机译：胡椒胡椒提取物的抗炎镇痛和解热活性。和Piper chaba Linn。
7. Anti-Inflammatory, Analgesic, and Antipyretic Activities of the Ethanol Extract of Piper interruptum Opiz. and Piper chaba Linn. [O] . Sireeratawong, Seewaboon, Itharat, Arunporn, Lerdvuthisopon, Nusiri, 2012

机译：胡椒胡椒提取物的抗炎，镇痛和解热活性。和Piper chaba Linn。

ISOLATION OF ALKAMIDES WITH DEATH RECEPTOR-ENHANCING ACTIVITIES FROM PIPER CHABA

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