RECENT PROGRESS IN THE SYNTHETIC STUDY OF AN ANTITUMOR MARINE MACROLIDE APLYRONINE A AND RELATED MOLECULES

摘要

Aplyronine A is a potent antitumor marine macrolide. The unique molecular structures of aplyronine A and its congeners, in conjunction with their potent biological activities, have made them attractive synthetic targets. This review discusses recent progress in the development of efficient routes to the synthesis of aplyronines and the related molecules.