Intramolecular [4+3]cycloadditions.towards a synthesis of widdrol

摘要

Certain substituted alkoxyallylic sulfones were alkylated and treated with Lewis acids to produce invylthionium ions that underwent intramolecular [4+3]cycloadditio reactions with a tethered furan.manipulation of the cycloadduct led to the synthesis of widdrol.other attempts to prepare the cycloadducts were made.but none were exceptionally better than the route using vinylthionimum ions as intermediates,Interesting aspects of the alkylation chemicstry of phenylthio-substituted alkoxyallylic sulfones are detailed as well.