4-DIMETHYLAMINOMETHYLENE-2-PYRAZINYL-5-(4H)-OXAZOLONE AS A SYNTHON FOR THE SYNTHESIS OF VARIOUS PYRAZOLES AND FUSED PYRIMIDINES~#

Kepe Vladimir; Kozjan Viktor

首页> 外文期刊>Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry >4-DIMETHYLAMINOMETHYLENE-2-PYRAZINYL-5-(4H)-OXAZOLONE AS A SYNTHON FOR THE SYNTHESIS OF VARIOUS PYRAZOLES AND FUSED PYRIMIDINES~#

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4-DIMETHYLAMINOMETHYLENE-2-PYRAZINYL-5-(4H)-OXAZOLONE AS A SYNTHON FOR THE SYNTHESIS OF VARIOUS PYRAZOLES AND FUSED PYRIMIDINES~#

机译：4-二甲基亚甲基亚甲基-2-吡嗪基-5-（4H）-恶唑酮作为合成各种吡咯和熔融嘧啶的合成物〜＃

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4-Dimethylaminomethylene-2-pyrazinyl-5(4H)-oxazolone (2) has been synthesized and transformed into various 1,4-disubstituted 1,2-dihydro-5H-pyrazol-5-ones (6) and fused pyrimidinones (8) by the reaction with selected hydrazines (5) and aminoheterocycles (7) .Products (6) and (8) have also been prepared from methyl 3-dimethylamino-2-(pyrazinylcarbonylamino)propenoate (3) and nitrogen-containing nucleophiles(5)or (7).

机译：已合成4-二甲基氨基亚甲基-2-吡嗪基-5（4H）-恶唑酮（2），并将其转化为各种1,4-二取代的1,2-二氢-5H-吡唑-5-酮（6）和稠合的嘧啶酮（8 ），通过与选定的肼（5）和氨基杂环（7）反应制得产物（6）和（8），还由3-二甲基氨基-2-（吡嗪基羰基氨基）丙酸甲酯（3）和含氮亲核试剂（5）制备）或（7）。

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《Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry》 |1999年第1期|共8页
作者
Kepe Vladimir; Kozjan Viktor;
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1. 4-DIMETHYLAMINOMETHYLENE-2-PYRAZINYL-5-(4H)-OXAZOLONE AS A SYNTHON FOR THE SYNTHESIS OF VARIOUS PYRAZOLES AND FUSED PYRIMIDINES~# [J] . Kepe Vladimir, Kozjan Viktor Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry . 1999,第1期

机译：4-二甲基亚甲基亚甲基-2-吡嗪基-5-（4H）-恶唑酮作为合成各种吡咯和熔融嘧啶的合成物〜＃
2. Synthesis, characterization and in vitro antimicrobial activity of novel fused pyrazolo[3,4- c ]pyridazine, pyrazolo[3,4- d ]pyrimidine, thieno[3,2- c ]pyrazole and pyrazolo[3′,4′:4,5]thieno[2,3- d ]pyrimidine derivatives [J] . Mohamed A. M. Abdel Reheim, Safaa M. Baker Chemistry central journal . 2017,第1期

机译：新型稠合吡唑并[3,4-c]哒嗪，吡唑并[3,4-d]嘧啶，噻吩并[3,2-c]吡唑和吡唑并[3'，4'：4的合成，表征及体外抗菌活性，5] thieno [2,3- d]嘧啶衍生物
3. Synthesis and Antimicrobial Activity of Some New Pyrazole, Fused Pyrazolo[3,4-d]-pyrimidine and Pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidine Derivatives [J] . Hamdi M. Hassaneen, Nada M. Abunada, Nadia G. Kandile, Molecules . 2008,第7期

机译：某些新型吡唑，熔融吡唑并[3,4-d]-嘧啶和吡唑并[4,3-e] [1,2,4]-三唑并[1,5-c]嘧啶衍生物的合成及抑菌活性
4. One-pot and Efficient Synthesis of Fused Heterocyclic Pyrimidines [C] . M. H. Mosslemin, M. R. Nateghi European Symposium on Organic Chemistry . 2009

机译：融合杂环嘧啶的一锅和高效合成
5. Target Based Design and Synthesis of Fused Pyrimidines in the Potential Treatment of Cancer and Opportunistic Infection [D] . Shah, Khushbu 2017

机译：基于目标的融合嘧啶类药物的设计和合成在潜在治疗癌症和机会性感染中的应用
6. Synthesis and Antimicrobial Activity of Some New Pyrazoles Fused Pyrazolo34-d-pyrimidine and 12-Dihydroimidazo-21-c124triazin-6-one Derivatives [O] . Sobhi Mohamed Gomha, Huwaida M.E. Hassaneen 2011

机译：某些新型吡唑熔融吡唑并34-d-嘧啶和12-二氢咪唑-21-c 124三嗪-6-一衍生物的合成及抑菌活性
7. Synthesis and Antimicrobial Activity of Some New Pyrazole, Fused Pyrazolo[3,4-d]-pyrimidine and Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine Derivatives [O] . Nada M. Abunada, Hamdi M. Hassaneen, Nadia G. K, 2013

机译：新型吡唑，稠合吡唑并[3,4-d] - 嘧啶和吡唑并[4,3-e] [1,2,4]三唑并[1,5-c]嘧啶衍生物的合成及抗菌活性

4-DIMETHYLAMINOMETHYLENE-2-PYRAZINYL-5-(4H)-OXAZOLONE AS A SYNTHON FOR THE SYNTHESIS OF VARIOUS PYRAZOLES AND FUSED PYRIMIDINES~#

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