Stereoselective C-allylation of 1-C-alkyl-2,3,4,6-tetra-O-benzyl-D-glucopyranoses with allyltrimethylsilane

摘要

The reaction of 1-C-alkyl-2,3,4,6-tetra-O-benzyl-D-glucopyanoses with allyltrimethylsilane in the presence of a catalytic amount of trimethylsilyl trifluoromethanesulfonate gave the corresponding C-allylated C-alkyl glucopyranosides in good yields. This C-allylation proceeded with high #alpha#-stereoselectivity.