LEWIS ACID CATALYZED DIASTEREOSELECTIVE 1,3-DIPOLAR CVCLOADDITION BETWEEN DIAZOACETOACETATE ENONES AND AZOMETHINE YLIDES

摘要

Silver acetate catalyzed 1,3-dipolar cycloaddition reactions of diazoacetoacetate enones and azomethine ylides produce tetrasubstituted pyrrolidines bearing a diazoacetoacetate functional array in excellent yields and diastcreoselectivities. The installment of the diazoacetoacetate functional array allows access to diverse hetereocyclic scaffolds.