Novel synthesis of 1-hydroxy-6-and-5-nitroindole-3-carbaldehydes,and their derivatives as daikon-phyto-alexin analogs

摘要

l-Hydroxy-6- and -5-nitroindole-3-carbaldehydes are prepared for the first time from l-methoxy-6- and -5-nitroindole-3-carbaldehydes,respectively,based on the discovery of novel methyl ether cleavage reaction.Utilizing them as common synthetic intermediates,syntheses of several daikon-phytoalexin analogs are achieved.