A new pterocarpan from erythrina fusca

摘要

A new pterocarpan,3-hydroxy-10-(3-hydroxy-3-methylbutyl)-9-methoxypterocarpan (1),together with seven known compounds,sandwicensin (2),erythrisenegalone (3),citflavanone (4),liquiritigenin (5),lonchocarpol A (6),lupinifolin (7) and 8-prenyldaidzein (8),were isolated from the stem bark of Erythrina fusca.The structure of 1 was determined on the basis of spectroscopic analyses.Among these compounds,lonchocarpol A (6)exhibited strongly antibacterial activities in vitro against Staphylococcus aureus,Bacillus subtilis and Enterococcus faecalis.Compounds (2,3,6 and 7) exhibited weakly antimycobacterial activity with minimum concentrations (MICs) of 100,50,50 and 25 mug/mL,respectively.