Oxidation products of strictosamide by iodosobenzene diacetate

摘要

Oxidation of strictosamide (1), a representative monoterpene indole alkaloid, by iodosobenzene diacetate (IBD) gave compounds (2 approx 6), among them the structure of 3 corresponded to an oxindole derived through oxidative cleavage between C-2 and C-3 of 1. A plausible mechanism of formation of 2 approx 6 from strictosamide (1) by IBD oxidation is proposed.