3-cyano-2-(N-cyanoimino)thiazolidine (3-cyano-NCT): an efficient electrophilic cyanating agent for activated methylene compounds

摘要

We found that 3-cyano-2-(N-cyanoimino)thiazolidine (3-cyano-NCT) is a novel electrophilic cyanating agent. Various activated methylene compounds were cyanated in moderate to good yields. Nitrile is an important synthetic intermediate for a variety of functional groups and is found in various pharmaceuticals and biologically active natural products.