Synthesis of spiro-fused nitrogen heterocyclic compounds via N-methoxy-N-acylnitrenium ions using phenyliodine (III) bis(trifluoroacetate) in trifluoroethanol

摘要

Spirodienones and spirodienes bearing the nitrogen atom bound to the spiro carbon have been synthesized from N-methoxy-(4-methoxyphenyl)amides and N-methoxyphenylamides, respectively, by the intramolecular ipso attack of a nitrenium ion generated with phenyliodine(III) bis(trifluoroacetate) in trifluoroethanol.