Regioselective preparation of pterin 6-triflate and its application to 6-substituted pterin synthesis

摘要

4-Butoxypteridine 6-triflate is prepared selectively from 4-butoxypteridine 8-oxide by a reaction with trifluoromethanesulfonic anhydride, and the triflate group can be replaced by various nucleophiles with functional groups.