ISOINDOLONE SYNTHESIS VIA INTRAMOLECULAR COUPLING OF BENZYLIC C-H BONDS WITH AMIDE N-H BONDS

摘要

Four 7-methyl-2-(8-quinolinyl)-2,3-dihydro-1H-isoindo]-1-ones were synthesized from 2,6-dimethyl-N-(8-quinolinyl)benzamides with exellent yields using Pd(OAc)2 as a catalyst, iodobenzene as an oxidant and AgOAc as an additive.