Treatment of specific symptoms improves health-related quality of life in patients with amyotrophic lateral sclerosis

摘要

Amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder, is characterized by motor neuron loss, which leads to muscle weakness and atrophy, paralysis and death. While riluzole, which is the only drug currently approved for the treatment of ALS, increases survival time, it does not improve the patient's functional status. Therefore, a multidisciplinary approach to managing specific ALS symptoms is necessary.