Potential for modest differences between sexes in antiretioviral therapy pharmacokinetics and adverse events

摘要

Women appear to be at higher risk for selected antiretroviral-associated adverse events than men Although the aetiology for a gender difference in antiretroviral tolerance among non-pregnant adults is unknown, possible contributing factors include gender-specific physiological and hormonal influences or unique pharmacokinetic profiles. The risk of selected toxicities may be influenced by pregnancy.