Rosuvastatin Is Effective to Decrease CD8 T-Cell Activation Only in HIV-Infected Patients With High Residual T-Cell Activation Under Antiretroviral Therapy

Weiss Laurence; Chevalier Mathieu F.; Assoumou Lambert; Paul Jean-Louis; Alhenc-Gelas Martine; Didier Celine; Taibi Said; Manea Elena-Maria; Campa Pauline; Girard Pierre-Marie; Costagliola Dominique

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Rosuvastatin Is Effective to Decrease CD8 T-Cell Activation Only in HIV-Infected Patients With High Residual T-Cell Activation Under Antiretroviral Therapy

机译：罗苏伐他汀仅在抗逆转录病毒疗法下具有高残留T细胞活化作用的HIV感染患者中有效降低CD8 T细胞活化作用

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《JAIDS: Journal of acquired immune deficiency syndromes 》 |2016年第4期| 共9页
作者
Weiss Laurence; Chevalier Mathieu F.; Assoumou Lambert; Paul Jean-Louis; Alhenc-Gelas Martine; Didier Celine; Taibi Said; Manea Elena-Maria; Campa Pauline; Girard Pierre-Marie; Costagliola Dominique;
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正文语种 eng
中图分类传染病 ;
关键词
HIV; immune activation; inflammation; ART; rosuvastatin;

机译：HIV;免疫激活;炎症;ART;瑞舒伐他汀;

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1. Rosuvastatin Is Effective to Decrease CD8 T-Cell Activation Only in HIV-Infected Patients With High Residual T-Cell Activation Under Antiretroviral Therapy [J] . Weiss Laurence, Chevalier Mathieu F., Assoumou Lambert, JAIDS: Journal of acquired immune deficiency syndromes . 2016 ,第4期

机译：罗苏伐他汀仅在抗逆转录病毒疗法下具有高残留T细胞活化作用的HIV感染患者中有效降低CD8 T细胞活化作用
2. CCR5+CD8 T-cell levels and monocyte activation precede the onset of acute coronary syndrome in HIV-infected patients on antiretroviral therapy [J] . Tarancon-Diez Laura, De Pablo-Bernal Rebeca S., Alvarez-Rios Ana I., Thrombosis and Haemostasis: Journal of the International Society on Thrombosis and Haemostasis . 2017 ,第6期

机译：CCR5 + CD8 T细胞水平和单核细胞活化在艾滋病毒治疗患者急性冠状动脉综合征的发作之前先发制于抗逆转录病毒治疗
3. Low CD4+ T-cell counts in HIV patients receiving effective antiretroviral therapy are associated with CD4+ T-cell activation and senescence but not with lower effector memory T-cell function. [J] . Fernandez S, Price P, McKinnon EJ, Clinical immunology: The official journal of the Clinical Immunology Society . 2006 ,第2期

机译：在接受有效抗逆转录病毒治疗的HIV患者中，CD4 + T细胞计数低与CD4 + T细胞活化和衰老有关，但与较低的效应记忆T细胞功能无关。
4. A NOVEL SCALABLE MANUFACTURING PLATFORM FOR T-CELL ACTIVATION AND EXPANSION IN ADOPTIVE T-CELL THERAPY [C] . Jian Ling Conference on advancing manufacture of cell and gene therapies . 2019

机译：适应性T细胞治疗中T细胞活化和扩展的新型可扩展制造平台
5. Increased density of class I major histocompatibility complex antigens and decreased density of T-cell differentiation antigens in the early stages of T-cell activation [D] . 松井良樹 1988

机译：在T细胞活化的早期，I类主要组织相容性复合抗原的密度增加，而T细胞分化抗原的密度降低
6. HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets Heightened CD8+ T Cell Activation and Increased Risk of Non-AIDS Morbidity and Mortality [O] . Sergio Serrano-Villar, Talia Sainz, Sulggi A. Lee, 2014

机译：尽管有效的抗逆转录病毒疗法但具有低CD4 / CD8比率的HIV感染者表现出改变的T细胞亚群增加的CD8 + T细胞活化以及增加的非艾滋病发病率和死亡率风险
7. CD8 T-Cell Activation Is Associated With Lipodystrophy and Visceral Fat Accumulation in Antiretroviral Therapy–Treated Virologically Suppressed HIV-Infected Patients [O] . Giovanni Guaraldi, Kety Luzi, Giusi Maria Bellistrì, 2013

机译：CD8 T细胞活化与抗逆转录病毒疗法治疗的病毒学抑制的HIV感染患者的脂肪营养不良和内脏脂肪蓄积有关

Rosuvastatin Is Effective to Decrease CD8 T-Cell Activation Only in HIV-Infected Patients With High Residual T-Cell Activation Under Antiretroviral Therapy

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