The effect of ion-pair formation combined with penetration enhancers on the skin permeation of loxoprofen

Hui Mei; Quan Peng; Yang Yingying; Fang Liang

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The effect of ion-pair formation combined with penetration enhancers on the skin permeation of loxoprofen

机译：离子对形成与渗透促进剂结合对洛索洛芬皮肤渗透的影响

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Context: Loxoprofen (LOXO) is a non-steroidal anti-inflammatory drug. Repeated oral administrations induce gastrointestinal side effects. Patches are a promising alternative.

机译：背景：洛索洛芬（LOXO）是一种非甾体类抗炎药。重复口服会引起胃肠道副作用。修补程序是有前途的替代方法。

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来源
《Drug delivery.》 |2016年第6期|共8页
作者
Hui Mei; Quan Peng; Yang Yingying; Fang Liang;
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正文语种 eng
中图分类药学;
关键词
Drug-in-adhesive patch; organic amine; pharmacodynamics; preformulation; transdermal drug delivery;

机译：贴剂;有机胺;药效学;预制剂;透皮给药;

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1. The effect of ion-pair formation combined with penetration enhancers on the skin permeation of loxoprofen [J] . Hui Mei, Quan Peng, Yang Yingying, Drug delivery. . 2016,第4a6期

机译：离子对形成与渗透促进剂结合对洛索洛芬皮肤渗透的影响
2. Dual-directional regulation of drug permeating amount by combining the technique of ion-pair complexation with chemical enhancers for the synchronous permeation of indapamide and bisoprolol in their compound patch through rabbit skin [J] . Song Wenting, Cun Dongmei, Quan Peng, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2015,第Null期

机译：通过离子对络合技术与化学增强剂的结合来双向调节药物的渗透量，从而使吲达帕胺和比索洛尔在他们的复合贴剂中同步渗透到兔皮中
3. Dual-directional regulation of drug permeating amount by combining the technique of ion-pair complexation with chemical enhancers for the synchronous permeation of indapamide and bisoprolol in their compound patch through rabbit skin [J] . Song Wenting, Cun Dongmei, Quan Peng, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2015,第Null期

机译：通过将离子对络合技术与化学增强剂相结合的双向调节药物渗透量，通过兔皮
4. Effects of Vehicles and Penetration Enhancers on Skin Permeation of Ondansetron [C] . Controlled Release Society annual meeting . 2004

机译：载体和渗透增强剂对ondansetron皮肤渗透的影响
5. Effects of the concentration of certain permeation enhancers on the permeation of Diltiazem HCl through cellulose membrane and human cadaver skin [D] . Dave, Masumi Umesh 2011

机译：某些渗透促进剂的浓度对盐酸地尔硫卓通过纤维素膜和人体尸体皮肤渗透的影响
6. Combined Use of N-Palmitoyl-Glycine-Histidine Gel and Several Penetration Enhancers on the Skin Permeation and Concentration of Metronidazole [O] . Sabrina Dahlizar, Mika Futaki, Akie Okada, 2018

机译：N-棕榈酰基-甘氨酸-组氨酸凝胶和几种渗透促进剂的组合使用对甲硝唑的皮肤渗透和浓度
7. Enhanced Skin Permeation of Salicylate by Ion-Pair Formation in Non-aqueous Vehicle and Further Enhancement by Ethanol and l-Menthol [O] . Mohammad Abu Hena Mostofa Kamal, Nahoko Iimura, Tomohiro Nabekura, 2006

机译：通过非含水载体中的离子对形成增强皮肤渗透水杨酸盐，并通过乙醇和L-Menthol进一步增强

The effect of ion-pair formation combined with penetration enhancers on the skin permeation of loxoprofen

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