Targeted delivery of etoposide to cancer cells by folate-modified nanostructured lipid drug delivery system

Zhang Shumei; Lu Caixia; Zhang Xiaoli; Li Junsheng; Jiang Hong

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Targeted delivery of etoposide to cancer cells by folate-modified nanostructured lipid drug delivery system

机译：叶酸修饰的纳米结构脂质药物递送系统靶向依托泊苷向癌细胞的递送

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Context: Cardiotoxicity and myelosuppression of etoposide (ETP) limited its clinical application. Targeted drug delivery system could deliver anticancer agents to the target cancerous cells, thus reducing their toxicity.

机译：背景：依托泊苷（ETP）的心脏毒性和骨髓抑制作用限制了其临床应用。靶向药物递送系统可以将抗癌剂递送至靶癌细胞，从而降低其毒性。

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来源
《Drug delivery.》 |2016年第6期|共8页
作者
Zhang Shumei; Lu Caixia; Zhang Xiaoli; Li Junsheng; Jiang Hong;
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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Box-Behnken design; etoposide; folic acid; nanostructured lipid carriers; tumor target;

机译：Box-Behnken设计;依托泊苷;叶酸;纳米结构脂质载体;肿瘤靶标;

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专利

1. Targeted delivery of etoposide to cancer cells by folate-modified nanostructured lipid drug delivery system [J] . Zhang Shumei, Lu Caixia, Zhang Xiaoli, Drug delivery. . 2016,第4a6期

机译：叶酸修饰的纳米结构脂质药物递送系统靶向依托泊苷向癌细胞的递送
2. Targeted delivery of etoposide to cancer cells by folate-modified nanostructured lipid drug delivery system [J] . Shumei Zhang, Caixia Lu, Xiaoli Zhang, Drug delivery. . 2016,第5期

机译：叶酸修饰的纳米结构脂质药物递送系统靶向依托泊苷向癌细胞的递送
3. Development of erythropoietin receptor-targeted drug delivery system against breast cancer using tamoxifen-loaded nanostructured lipid carriers [J] . Chaw Yee Beh, Chee Wun How, Jhi Biau Foo, Drug Design, Development and Therapy . 2017,第5期

机译：使用载有他莫昔芬的纳米结构脂质载体开发针对乳腺癌的促红细胞生成素受体靶向药物递送系统
4. Engineered Extracellular Vesicles with Synthetic Lipids via Membrane Fusion to Establish Efficient and Targeted Drug and Gene Delivery [C] . Yong Yu Jhan, David Moore, Shreedevi Arun Kumar, Society for Biomaterials annual meeting and exposition . 2018

机译：通过膜融合工程合成脂质的细胞外囊泡，以建立有效的靶向药物和基因递送
5. Fibrinogen-coated lipid-based drug delivery systems: A novel approach for targeted delivery of anti-cancer taxanes to tumors. [D] . Jakate, Abhijeet S. 2003

机译：纤维蛋白原包衣的脂质基药物递送系统：一种将抗癌紫杉烷类药物靶向递送至肿瘤的新方法。
6. Development of erythropoietin receptor-targeted drug delivery system against breast cancer using tamoxifen-loaded nanostructured lipid carriers [O] . Chaw Yee Beh, Chee Wun How, Jhi Biau Foo, 2017

机译：使用载有他莫昔芬的纳米结构脂质载体开发针对乳腺癌的促红细胞生成素受体靶向药物递送系统
7. Targeted delivery of etoposide to cancer cells by folate-modified nanostructured lipid drug delivery system [O] . Shumei Zhang, Caixia Lu, Xiaoli Zhang, 2016

机译：通过叶酸改性的纳米结构脂质药物输送系统将依托泊苷的依次递送到癌细胞
8. Development of Lipid-based Nanoparticles for in vivo Targeted Delivery of Imaging Agents into Breast Cancer Cells [R] . Popov, A. V., Sykulev, Y. 2010

机译：用于体内靶向递送成像剂进入乳腺癌细胞的基于脂质的纳米颗粒的开发

Targeted delivery of etoposide to cancer cells by folate-modified nanostructured lipid drug delivery system

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