Liposomal co-delivery of daptomycin and clarithromycin at an optimized ratio for treatment of methicillin-resistant Staphylococcus aureus infection

Li Yanhong; Su Tingting; Zhang Yan; Huang Xingliang; Li Jing; Li Chong

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Liposomal co-delivery of daptomycin and clarithromycin at an optimized ratio for treatment of methicillin-resistant Staphylococcus aureus infection

机译：达托霉素和克拉霉素的脂质体联合分娩优化比例治疗耐甲氧西林的金黄色葡萄球菌感染

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Context: Pathogen evolution currently outpaces novel drug development, and because development of new antibiotics is pending, combination therapy with existing drugs may provide effective alternative treatments.

机译：背景：病原体的进化目前超过了新药的开发，而且由于新抗生素的开发尚在进行中，因此与现有药物联合治疗可能会提供有效的替代疗法。

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《Drug delivery.》 |2015年第8期|共11页
作者
Li Yanhong; Su Tingting; Zhang Yan; Huang Xingliang; Li Jing; Li Chong;
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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Antibiotics; combination chemotherapy; liposome; severe infections;

机译：抗生素;联合化疗;脂质体;严重感染;

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专利

1. Liposomal co-delivery of daptomycin and clarithromycin at an optimized ratio for treatment of methicillin-resistant Staphylococcus aureus infection [J] . Li Yanhong, Su Tingting, Zhang Yan, Drug delivery. . 2015,第1a8期

机译：达托霉素和克拉霉素的脂质体联合分娩优化比例治疗耐甲氧西林的金黄色葡萄球菌感染
2. Treatment of methicillin-resistant staphylococcus aureus infections with a minimal inhibitory concentration of 2 μg/mL to vancomycin: Old (trimethoprim/sulfamethoxazole) versus new (daptomycin or linezolid) agents [Staphylococcus aureus resistante a meticilina con una concentración mínima inhibitoria de 2 μg/ml para vancomicina: Agentes viejos (trimetoprim/sulfametoxazol) contra agentes nuevos (daptomicina o linezolida)] [J] . The annals of pharmacotherapy . 2012,第12期

机译：对万古霉素的最低抑菌浓度为2μg/ mL的耐甲氧西林金黄色葡萄球菌感染的治疗：旧药（甲氧苄啶/磺胺甲恶唑）与新药（达托霉素或利奈唑胺）[金黄色葡萄球菌抗药性，无浓缩菌素/微球菌抑制剂2 ml para vancomicina：Agentes viejos（trimetoprim / sulfametoxazol）对立物neuvos（daptomicina o linezolida）]
3. Monotherapy with Vancomycin or Daptomycin versus Combination Therapy with beta-Lactams in the Treatment of Methicillin-Resistant Staphylococcus Aureus Bloodstream Infections: A Retrospective Cohort Analysis [J] . Progress in Artificial Intelligence . 2020,第2期

机译：用Vancomycin或达达霉素的单药治疗与β-内酰胺的组合治疗治疗甲氧西林抗葡萄球菌血液感染：回顾性队列分析
4. THE EMERGENCE OF A BAD BUG: TREATMENT, INFECTION CONTROL PUBLIC HEALTH CHALLENGES OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) [C] . Jeffrey B. Bender Canadian Veterinary Medical Association Convention . 2009

机译：出现坏虫子：耐甲氧西林金黄色葡萄球菌的治疗，感染控制和公共卫生挑战（MRSA）
5. A retrospective study to evaluate the efficacy of trimethoprim/sulfamethoxazole (TMP/SMX) compared to Daptomycin or Linezolid for the treatment of infections due to methicillin-resistant Staphylococcus aureus (MRSA). [D] . Poona Murari, Aparna Lakshmi. 2012

机译：回顾性研究评估甲氧苄氨嘧啶/磺胺甲恶唑（TMP / SMX）与达托霉素或利奈唑胺相比在治疗耐甲氧西林金黄色葡萄球菌（MRSA）感染中的疗效。
6. Adjunctive Rifampin Is Crucial to Optimizing Daptomycin Efficacy against Rabbit Prosthetic Joint Infection Due to Methicillin-Resistant Staphylococcus aureus [O] . Azzam Saleh-Mghir, Claudette Muller-Serieys, Aurélien Dinh, 2011

机译：辅助性利福平对于优化达托霉素对耐甲氧西林金黄色葡萄球菌的兔假体关节感染的疗效至关重要
7. 286. Exploratory Cost-Effectiveness Analysis for Treatment of Methicillin-Resistant Staphylococcus aureus Bloodstream Infections: Are Daptomycin and Linezolid Favored over Vancomycin and Other Antibiotics? [O] . Michelle Vu, Kenneth Smith, Sherrie L Aspinall, 2020

机译：286.治疗甲氧胞素抗性金黄色葡萄球菌血液感染的探索性成本效果分析：达摩霉素和LINEZOLID青霉素，对万古霉素和其他抗生素有利吗？

Liposomal co-delivery of daptomycin and clarithromycin at an optimized ratio for treatment of methicillin-resistant Staphylococcus aureus infection

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