Dehydechlorination of 4-Hydroxy-3,5-di-tert-butylbenzylidene Chloride with Aprotic Nonionogenic Reagents

摘要

We showed previously that 4-hydroxy-3,5-di-tert-butylbenzylidene chloride (I) reacted with nonionogenic aprotic reagents,such as triethyl orthoformate (II) [1] and esters of phosphorus(III) acids (HI) [2],via nucleophilic displacement and underwent dechloro-alkoxylation and dechlorophosphorylation to form ace-tal and diphosphonate,respectively.We studied previously unknown reactions of gem-dichloride I with ethylene oxide (TV),vinyl ethyl ether (V),N,N,N',N'-tetramethylmethanediamine (VI),and dimethyl(4-hydroxy-3,5-di-tert-butylbenzyl)amine (VII).