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Formation Kinetics of Gold Nanoparticles in the Galactomannan Polysaccharide Matrix

机译:半乳甘露聚糖多糖基质中金纳米颗粒的形成动力学

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摘要

Gold nanoparticles and nanocomposites based on them are finding more and more extensive use as highly effective catalysts of various chemical processes [1], optical sensors of biospecific interactions [2], agents for the targeted drug delivery [2] and photo-thermolysis of cancer cells [3], inhibitors of autoimmune diseases [4], etc. However, the problem of thermodynamic instability of nanoparticles caused by excess of their surface energy has not still been ultimately solved [5, 6]. This problem is addressed using stabilizing polymeric matrices of synthetic and natural origin, in particular, polysaccharides, which impart a specific set of additional physicochemical and biological properties to nanoparticles [7, 8].
机译:金纳米颗粒和基于它们的纳米复合材料正被越来越广泛地用作各种化学过程的高效催化剂[1],生物特异性相互作用的光学传感器[2],用于靶向药物递送的试剂[2]和癌症的光热分解细胞[3],自身免疫性疾病的抑制剂[4]等。然而,由其表面能过多引起的纳米粒子的热力学不稳定性问题尚未得到最终解决[5,6]。使用稳定的合成和天然来源的聚合物基质(特别是多糖)可解决此问题,多糖可赋予纳米颗粒特定的一组额外的物理化学和生物学特性[7,8]。

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