Changes in the excitability of the rat pulmonary vein myocardium induced by adrenergic stimulation.

摘要

Heart pathologies are accompanied by alternations in the bioelectrical activity of the myocardium, enhancement or loss of excitability [1]. The phenom ena are often local and cover only certain portions of the heart, which enhances the electrical heterogeneity of the myocardium [2]. Enhancement of the electrical heterogeneity is a proarythmogenic factor [3]. Para sympathetic and sympathetic stimulations also enhance electrical heterogeneity, which increases the incidence of arrhythmias, including atrial fibrillation (AF) [4].