Effectiveness and Safety of Tenofovir Disoproxil Fumarate in Chronic Hepatitis B: A 3-Year, Prospective, Real-World Study in France

Marcellin Patrick; Zoulim Fabien; Hezode Christophe; Causse Xavier; Roche Bruno; Truchi Regine; Pauwels Arnaud; Ouzan Denis; Dumortier Jerome; Pageaux Georges-Philippe; Bourliere Marc; Riachi Ghassan; Zarski Jean-Pierre; Cadranel Jean-Francois; Tilliet Valerie; Stern Christiane; Petour Pascal; Libert Olivier; Consoli Silla M.; Larrey Dominique

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Effectiveness and Safety of Tenofovir Disoproxil Fumarate in Chronic Hepatitis B: A 3-Year, Prospective, Real-World Study in France

机译：替诺福韦富马酸替诺福韦酯在慢性乙型肝炎中的有效性和安全性：一项为期3年的前瞻性法国现实世界研究

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摘要

Tenofovir disoproxil fumarate (TDF) demonstrated potent and sustainable antiviral efficacy and a good safety profile in patients with chronic hepatitis B (CHB) in controlled clinical trials. Real-world data are important to confirm effectiveness and safety data in patient populations encountered in routine clinical practice.

机译：在慢性乙型肝炎（CHB）患者的对照临床试验中，替诺福韦酯富马酸泰索非尔（TDF）表现出有效且可持续的抗病毒功效，并具有良好的安全性。实际数据对于确认常规临床实践中遇到的患者人群的有效性和安全性数据很重要。

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来源
《Digestive Diseases and Sciences》 |2016年第10期|共12页
作者
Marcellin Patrick; Zoulim Fabien; Hezode Christophe; Causse Xavier; Roche Bruno; Truchi Regine; Pauwels Arnaud; Ouzan Denis; Dumortier Jerome; Pageaux Georges-Philippe; Bourliere Marc; Riachi Ghassan; Zarski Jean-Pierre; Cadranel Jean-Francois; Tilliet Valerie; Stern Christiane; Petour Pascal; Libert Olivier; Consoli Silla M.; Larrey Dominique;
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正文语种 eng
中图分类消化系及腹部疾病;
关键词
HBV; Tenofovir; Routine practice; Real-world;

机译：乙肝病毒;替诺福韦;常规治疗;现实世界;

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1. Effectiveness and Safety of Tenofovir Disoproxil Fumarate in Chronic Hepatitis B: A 3-Year, Prospective, Real-World Study in France [J] . Marcellin Patrick, Zoulim Fabien, Hezode Christophe, Digestive Diseases and Sciences . 2016,第10期

机译：替诺福韦富马酸替诺福韦酯在慢性乙型肝炎中的有效性和安全性：一项为期3年的前瞻性法国现实世界研究
2. Treatment Outcome and Renal Safety of 3-Year Tenofovir Disoproxil Fumarate Therapy in Chronic Hepatitis B Patients with Preserved Glomerular Filtration Rate [J] . In Suk Min, Chang Hun Lee, Ik Sang Shin, Gut and Liver . 2019,第1期

机译：保留肾小球滤过率的慢性乙型肝炎患者3年替诺福韦富马酸替诺福酯治疗的治疗结果和肾脏安全
3. Improved Bone and Renal Safety at 1 Year after Switching from Tenofovir Disoproxil Fumarate (TDF) to Tenofovir Alafenamide (TAF): Results from 2 Phase 3 Studies in HBeAg-positive and HBeAg-negative Patients with Chronic Hepatitis B (CHB) [J] . Pan Calvin Q., Brunetto Maurizia R., Hui Aric Josun, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2017,第Suppla1期

机译：从替诺福韦毒性富马酸核（TDF）转向替诺福韦·阿拉芬酰胺（TAF）后1年改善骨骼和肾脏安全性：结果来自2阶段3研究的HBEAG阳性和HBEAG阴性慢性乙型肝炎（CHB）的研究结果
4. Modeling and simulation for dynamics of tenofovir disoproxil fumarate anti-HBV infection therapy [C] . Xiao Chen, Jianlong Qiu, Weiqi Qin, Chinese Automation Congress . 2017

机译：替诺福韦富马酸替诺福韦抗乙肝病毒感染治疗动力学建模与仿真
5. Treatment of human immunodeficiency virus with zidovudine and tenofovir regimen in India: A comparative effectiveness study. [D] . Thuppal, Sowmyanarayanan. 2015

机译：在印度用齐多夫定和替诺福韦方案治疗人类免疫缺陷病毒：比较效果研究。
6. Effectiveness and Safety of Tenofovir Disoproxil Fumarate in Chronic Hepatitis B: A 3-Year Prospective Real-World Study in France [O] . Patrick Marcellin, Fabien Zoulim, Christophe Hézode, -1

机译：替诺福韦富马酸替诺福韦酯在慢性乙型肝炎中的有效性和安全性：一项为期3年的前瞻性法国现实世界研究
7. Effectiveness and Safety of Tenofovir Disoproxil Fumarate in Chronic Hepatitis B: A 3-Year, Prospective, Real-World Study in France [O] . 2016

机译：替诺福韦富马酸替诺福韦酯在慢性乙型肝炎中的有效性和安全性：一项为期3年的前瞻性法国现实世界研究

Effectiveness and Safety of Tenofovir Disoproxil Fumarate in Chronic Hepatitis B: A 3-Year, Prospective, Real-World Study in France

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