Enhanced gastric ghrelin-induced c-kit protein expression in rats with gastric outlet obstruction

摘要

Dear Editor,We reported in the April issue of Digestive Diseases and Sciences that rats with gastric outlet obstruction (GOO) had an enhanced mRNA expression of c-kit, a marker of interstitial cells of Cajal (ICC), in the stomach with an increased level of ghrelin production [1]. However, the distribution of c-Kit protein expression inhe stomach was not shown. Now, we have completed the additional experiments to clarify this point.