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What symptoms predict the diagnosis of autism or PDD-NOS in infants and toddlers with developmental delays using the Baby and Infant Screen for aUtIsm Traits.

机译:使用婴儿和婴儿筛查自闭症特征,哪些症状可预测患有发育迟缓的婴幼儿自闭症或PDD-NOS的诊断。

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PURPOSE: Autism Spectrum Disorders (ASD) are characterized by life-long and severe symptoms such as stereotypies, social skills deficits and language delays. Previous research has demonstrated that children who receive early intensive behavioural intervention have a better prognosis than those who do not receive services. It is for this reason that assessments designed specifically for early identification of ASD are of paramount important. METHOD: In Study 1, 957 infants with autism, PDD-NOS and atypical development were evaluated using an assessment screener for ASD traits, the Baby and Infant Screen for aUtIsm Traits (BISCUIT). In Study 2, only those with an autism or PDD-NOS diagnosis were evaluated. RESULTS: The BISCUIT was found to have an excellent overall classification rate for children in the target population. A sub-set of BISCUIT items was found that distinguished children with ASD from atypically developing children. Items were also found which could accurately predict autism vs PDD-NOS diagnosis. CONCLUSIONS: These data suggest that the core features of ASD are distinct and can be identified early in life. Furthermore, the presence of specific core behaviours can allow for a more accurate clinical and diagnostic picture for young children with autism or PDD-NOS vs general developmental delays.
机译:目的:自闭症谱系障碍(ASD)的特征是终身和严重的症状,如刻板印象,社交技能缺陷和语言延迟。先前的研究表明,接受早期强化行为干预的儿童的预后要比不接受服务的儿童更好。出于这个原因,专门为早期识别ASD而设计的评估至关重要。方法:在研究1中,对957名自闭症,PDD-NOS和非典型发育的婴儿进行了ASD特征评估筛查,即自闭性婴儿和婴儿筛查(BISCUIT)。在研究2中,仅对患有自闭症或PDD-NOS诊断的患者进行评估。结果:发现BISCUIT对目标人群中的儿童具有良好的总体分类率。发现BISCUIT项目的子集可以将ASD儿童与非典型儿童区分开。还发现了可以准确预测自闭症与PDD-NOS诊断的项目。结论:这些数据表明ASD的核心特征是独特的,并且可以在生命早期被发现。此外,特定的核心行为的存在可以为患有自闭症或PDD-NOS的幼儿提供更准确的临床和诊断图片,而不是一般的发育延迟。

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