O n-butil cianoacrilato na lobectomia pulmonar parcial em felinos. Estudo experimentalThe n-butyl cyanoacrilate in partial lung lobectomy in cats. Experimental study

摘要

The n-butyl cyanoacrilate tissue adhesive was used in this study aiming to verify the viability of its use for hemostasis and to avoid air leakage in partial lung lobectomy. Six healthy adult female domestic shorthair cats, weight range of three kg were submitted to an intercostal thoracotomy with partial lung lobectomy using n-butyl cyanoacrilate to close the lobe. After 21 days they were submitted to another thoracotomy to collect a fragment of the lung where the adhesive was applied to a histopathological study. Chest films were taken pre and post partial lung lobectomy and at two, seven, 14 and 21 days as a follow up procedure. Radiographical and clinical changes such as residual pneumothorax, increase in pulmonary density, subcutaneous emphysema and apathy were corrected in due time, not compromising the study. The histopathology results showed an inflammatory reaction with mononuclear prevailing, neovascularization, spread of connective tissue and small areas of emphysema and atelectasy, with no significant clinical signs. The conclusion was that the cyanoacrilate adhesive may control the air leakage and hemorrhage and can be an option for sutureless partial lung lobectomy.