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Depressive Symptoms during an Acute Schizophrenic Episode: Frequency and Clinical Correlates

机译:急性精神分裂症发作期间的抑郁症状:频率和临床相关性

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Introduction. Depressive symptoms are common in schizophrenia and are associated with poorer functioning, lower quality of life, and an elevated risk of suicidal behaviour. There are few studies on the occurrence and correlates of these symptoms in acutely ill patients with schizophrenia. Method. 72 acutely ill patients with schizophrenia were assessed for depression using the Calgary Depression Scale for Schizophrenia (CDSS). A cut-off score of >6 on the CDSS was used to identify clinically significant depressive symptoms. The relationship between depression and illness variables, including psychotic symptom dimensions as measured by the Positive and Negative Syndrome Scale for Schizophrenia (PANSS), was examined. Results. Eleven (15.3%) patients had clinically significant depressive symptoms. These patients scored higher on the positive and general psychopathology scales of the PANSS and had higher rates of suicidal behavior and poorer functioning. The severity of depressive symptoms was positively correlated with the PANSS positive subscale and negatively correlated with the PANSS negative subscale. Discussion. These findings confirm previous reports that depressive symptoms in active schizophrenia is related to the severity of positive psychotic symptoms and is a risk factor for suicidal behaviour in these patients.
机译:介绍。抑郁症状在精神分裂症中很常见,并且与功能较差,生活质量降低和自杀行为的风险升高有关。急性精神分裂症患者中这些症状的发生及其相关性的研究很少。方法。使用卡尔加里精神分裂症抑郁量表(CDSS)对72名急性精神分裂症患者进行了抑郁评估。 CDSS的临界值> 6,用于识别临床上显着的抑郁症状。研究了抑郁症和疾病变量之间的关系,包括精神分裂症的阳性和阴性综合症量表(PANSS)所测得的精神症状的维度。结果。十一名(15.3%)患者有临床上明显的抑郁症状。这些患者在PANSS的阳性和一般心理病理学评分上得分较高,并且自杀行为发生率较高且功能较差。抑郁症状的严重程度与PANSS阳性子量表呈正相关,与PANSS阴性子量表负相关。讨论。这些发现证实了以前的报道,即活动性精神分裂症的抑郁症状与精神病学阳性症状的严重程度有关,并且是这些患者自杀行为的危险因素。

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