Multiphase enantioselective Kharasch-Sosnovsky allylic oxidation based on neoteric solvents, copper complexes of ditopic ligands

摘要

Recoverable multiphase enantioselective catalytic systems for the Kharasch-Sosnovsky oxidation of cycloalkenes with tert-butyl peroxybenzoate are described, based on the use of [BMIM][PF _6] and a new solvent derived from glycerol as the catalyst reservoir phases, and chiral copper complexes with different ligands from the bis(oxazoline) family. The best results are obtained with the glycerol-derived solvent and a recently described azabisoxazoline- based ditopic ligand, allowing up to four uses of the catalytic phase with good results.