Chiral phosphonite, phosphite and phosphoramidite η~6-arene- ruthenium(ii) complexes: Application to the kinetic resolution of allylic alcohols

摘要

The synthesis and characterization of chiral arene-ruthenium complexes [RuCl_2(η~6-arene){(R)-PR(binaphthoxy)}] (arene = benzene (1), p-cymene (2), mesitylene (3); R = Ph (a), OPh (b), piperidyl (c)) are described. Derivatives 1-3 have been employed to promote the kinetic resolution of allylic alcohols through a redox-isomerization process. As a general trend, the best selectivities are attained with the more sterically hindered catalysts i.e. those containing p-cymene or mesitylene ligands.