The proteolytic activity of pregnancy-associated plasma protein-A is potentially regulated by stanniocalcin-1 and-2 during human ovarian follicle development

Jepsen Malene R.; Kloverpris Soren; Botkjaer Jane A.; Wissing Marie L.; Andersen Claus Y.; Oxvig Claus

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The proteolytic activity of pregnancy-associated plasma protein-A is potentially regulated by stanniocalcin-1 and-2 during human ovarian follicle development

机译：妊娠相关血浆蛋白-A的蛋白水解活性可能在人卵泡发育过程中受锡钙蛋白-1和-2调节。

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STUDY QUESTION: Is the proteolytic activity of pregnancy-associated plasma protein-A (PAPP-A) regulated by the stanniocalcins (STC1 and STC2) during human follicle maturation?

机译：研究问题：在人卵泡成熟过程中，妊娠相关血浆蛋白-A（PAPP-A）的蛋白水解活性受到锡钙蛋白（STC1和STC2）的调节吗？

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《Human Reproduction》 |2016年第4期|共9页
作者
Jepsen Malene R.; Kloverpris Soren; Botkjaer Jane A.; Wissing Marie L.; Andersen Claus Y.; Oxvig Claus;
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正文语种 eng
中图分类人体生理学;
关键词
human follicles; follicle development; pregnancy-associated plasma protein-A; insulin-like growth factor system; stanniocalcin;

机译：人卵泡;卵泡发育;妊娠相关血浆蛋白A;胰岛素样生长因子系统;锡钙素;

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1. The proteolytic activity of pregnancy-associated plasma protein-A is potentially regulated by stanniocalcin-1 and-2 during human ovarian follicle development [J] . Jepsen Malene R., Kloverpris Soren, Botkjaer Jane A., Human Reproduction . 2016,第4期

机译：妊娠相关血浆蛋白-A的蛋白水解活性可能在人卵泡发育过程中受锡钙蛋白-1和-2调节。
2. Effect of pregnancy-associated plasma protein-A (PAPP-A) single-nucleotide polymorphisms on the level and activity of PAPP-A and the hormone profile in fluid from normal human small antral follicles [J] . Botkjaer Jane Alro, Borgbo Tanni, Kloverpris Soren, Fertility and Sterility: Official Journal of the American Fertility Society, Pacific Coast Fertility Society, and the Canadian Fertility and Andrology Society . 2016,第7期

机译：妊娠相关血浆蛋白A（PAPP-A）单核苷酸多态性对正常人小窦卵泡液中PAPP-A的水平和活性以及激素谱的影响
3. Author Correction: A common variant of the pregnancy-associated plasma protein-A (PAPPA) gene encodes a protein with reduced proteolytic activity towards IGF-binding proteins [J] . J. A. B?tkj?r, P. R. Noer, Claus Oxvig, Scientific reports. . 2019,第1期

机译：作者校正：妊娠相关血浆蛋白-A（Pappa）基因的常见变体编码蛋白质，其朝向IGF结合蛋白的蛋白水解活性降低
4. Domestic ruminants as models for the elucidation of the mechanisms controlling ovarian follicle development in humans [C] . B. K. Campbell, C. Souza, J. Gong, International Symposium on Reproduction in Domestic Ruminants . 2003

机译：国内反刍动物作为阐明控制人类卵巢卵泡发育机制的模型
5. Real-time RT-PCR quantification of pregnancy-associated plasma protein-A gene expression in granulosa and theca cells: Effects of hormones in vitro. [D] . Aad, Pauline Youssef. 2005

机译：实时RT-PCR量化与颗粒细胞和卵泡膜细胞中妊娠相关的血浆蛋白A基因表达：激素在体外的影响。
6. Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A [O] . Søren Kløverpris, Jakob H. Mikkelsen, Josefine H. Pedersen, 2015

机译：Stanniocalcin-1有效抑制金属蛋白酶妊娠相关血浆蛋白-A的蛋白水解活性。
7. Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ovine, Bovine, Porcine, and Equine Ovarian Follicles:Involvement in IGF Binding Protein-4 Proteolytic Degradation and mRNA Expression During Follicular Development [O] . Mazerbourg, Sabine, Overgaard, Michael T, Oxvig, Claus, 2001

机译：在卵，牛，猪和马卵巢卵泡中的妊娠相关血浆蛋白-a（papp-a）：在卵泡发育过程中参与IGF结合蛋白-4蛋白水解降解和mRNa表达

The proteolytic activity of pregnancy-associated plasma protein-A is potentially regulated by stanniocalcin-1 and-2 during human ovarian follicle development

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