Diminished ovarian reserve is not observed in infertility patients with high normal CGG repeats on the fragile X mental retardation 1 (FMR1) gene

Schufreider Ann; McQueen Dana B.; Lee Sang Mee; Allon Rachel; Uhler Meike L.; Davie Jocelyn; Feinberg Eve C.

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Diminished ovarian reserve is not observed in infertility patients with high normal CGG repeats on the fragile X mental retardation 1 (FMR1) gene

机译：在脆性X智力低下1（FMR1）基因上具有高正常CGG重复数的不育患者中未观察到卵巢储备减少

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STUDY QUESTION: Does an association exist between high normal numbers of CGG trinucleotide repeats on the fragile X mental retardation 1 (FMR1) gene and diminished ovarian reserve (DOR)?

机译：研究问题：脆弱的X智力低下1（FMR1）基因上正常高水平的CGG三核苷酸重复序列与卵巢储备（DOR）减少之间是否存在关联？

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来源
《Human Reproduction》 |2015年第11期|共7页
作者
Schufreider Ann; McQueen Dana B.; Lee Sang Mee; Allon Rachel; Uhler Meike L.; Davie Jocelyn; Feinberg Eve C.;
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正文语种 eng
中图分类人体生理学;
关键词
infertility; FMR1 gene; anti-Mullerian hormone; ovarian reserve; genetic counseling;

机译：不孕症;FMR1基因;抗Mullerian激素;卵巢储备;遗传咨询;

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1. Diminished ovarian reserve is not observed in infertility patients with high normal CGG repeats on the fragile X mental retardation 1 (FMR1) gene [J] . Schufreider Ann, McQueen Dana B., Lee Sang Mee, Human Reproduction . 2015,第11期

机译：在脆性X智力低下1（FMR1）基因上具有高正常CGG重复数的不育患者中未观察到卵巢储备减少
2. Variable expression of the Fragile X Mental Retardation 1 (FMR1) gene in patients with premature ovarian failure syndrome is not dependent on number of (CGG)_n triplets in exon 1 [J] . J. Schuettler, Z. Peng, J. Zimmer, Human Reproduction . 2011,第5期

机译：卵巢早衰综合征患者中脆弱X智力低下1（FMR1）基因的可变表达与外显子1中（CGG）n _{n三联体的数目无关}
3. The significance of fragile X mental retardation gene 1 CGG repeat sizes in the normal and intermediate range in women with primary ovarian insufficiency [J] . VoorhuisM., Onland-MoretN.C., JanseF., Human Reproduction . 2014,第7期

机译：原发性卵巢功能不全的女性在正常和中等范围内的脆弱X智力低下基因1 CGG重复大小的意义
4. Basal ovarian reserve tests do not estimate follicular development in stimulated cycles of young infertile patients [C] . AH Rustu Ergur, Levent Tutuncu, Ozgur Dundar, World Congress on Fertility and Sterility . 2004

机译：基础卵巢储备试验没有估计患者患者刺激患者的卵泡发育
5. Molecular Consequences of Expanded CGG Repeats in the Human FMR1 Gene: R-loops, Methylation, and DNA Sequencing. [D] . Loomis, Erick Welder. 2013

机译：人类FMR1基因中扩增的CGG重复序列的分子后果：R环，甲基化和DNA测序。
6. The significance of FMR1 CGG repeats in Chinese women with premature ovarian insufficiency and diminished ovarian reserve [O] . Ruiyi Tang, Qi Yu 2020

机译：FMR1 CGG重复在高卵巢功能不全和卵巢储备减少的中国女性中的重要性
7. Diminished ovarian reserve is not observed in infertility patients with high normal CGG repeats on the fragile X mental retardation 1 (FMR1) gene [O] . Ann Schufreider, Dana B. McQueen, Sang Mee Lee, 2015

机译：在脆弱的X精神迟滞1（FMR1）基因上，不孕症患者在不孕症患者中未经卵巢储备减少卵巢储备
8. PARK2, a Large Common Fragile Site Gene, is Part of a Stress Response Network in Normal Cells that is Disrupted During the Development of Ovarian Cancer; Final addendum rept. 15 Dec 2006-14 Dec 2007 [R] . Smith, D. I., Zhu, Y. 2008

机译：paRK2是一种大型常见的脆性位点基因，是卵巢癌发生过程中被破坏的正常细胞应激反应网络的一部分;最后的补遗。 2006年12月15日至2007年12月14日

Diminished ovarian reserve is not observed in infertility patients with high normal CGG repeats on the fragile X mental retardation 1 (FMR1) gene

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