Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles

Fiorentino Francesco; Bono Sara; Biricik Anil; Nuccitelli Andrea; Cotroneo Ettore; Cottone Giuliano; Kokocinski Felix; Michel Claude-Edouard; Minasi Maria Giulia; Greco Ermanno

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Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles

机译：下一代测序技术在胚泡植入前基因筛查周期中囊胚非整倍性综合筛查中的应用

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STUDY QUESTION: Can next-generation sequencing (NGS) techniques be used reliably for comprehensive aneuploidy screening of human embryos from patients undergoing IVF treatments, with the purpose of identifying and selecting chromosomally normal embryos for transfer?

机译：研究问题：下一代测序（NGS）技术能否可靠地用于接受IVF治疗的患者的人类胚胎的综合非整倍性筛选，以鉴定和选择染色体正常的胚胎进行移植？

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《Human Reproduction》 |2014年第12期|共12页
作者
Fiorentino Francesco; Bono Sara; Biricik Anil; Nuccitelli Andrea; Cotroneo Ettore; Cottone Giuliano; Kokocinski Felix; Michel Claude-Edouard; Minasi Maria Giulia; Greco Ermanno;
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正文语种 eng
中图分类人体生理学;
关键词
comprehensive chromosome screening; preimplantation genetic screening; array-comparative genomic hybridization; next-generation sequencing; clinical outcomes;

机译：综合染色体筛选;植入前遗传筛选;阵列比较基因组杂交;下一代测序;临床结果;

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专利

1. Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles [J] . Fiorentino Francesco, Bono Sara, Biricik Anil, Human Reproduction . 2014,第12期

机译：下一代测序技术在胚泡植入前基因筛查周期中囊胚非整倍性综合筛查中的应用
2. Impact of blastocyst biopsy and comprehensive chromosome screening technology on preimplantation genetic screening: a systematic review of randomized controlled trials [J] . Dahdouh Elias M., Balayla Jacques, Antonio Garcia-Velasco Juan Reproductive biomedicine online . 2015,第3期

机译：胚泡活检和综合染色体筛查技术对植入前基因筛查的影响：随机对照试验的系统评价
3. Application of next-generation sequencing for 24-chromosome aneuploidy screening of human preimplantation embryos [J] . Haiyan Zheng, Hua Jin, Lian Liu, Molecular cytogenetics . 2015,第1期

机译：下一代测序在人类植入前胚胎的24染色体非整倍性筛选中的应用
4. A review of commercially available non-invasive vascular screening technologies for clinical applications [C] . Sohani Vahid, Zahedi Edmond, Chellappan Kalaivani, 2012 IEEE EMBS Conference on Biomedical Engineering and Sciences. . 2012

机译：商用无创血管筛查技术的临床应用综述
5. A literature review on the effect preimplantation genetic screening in combination with in vitro fertilization has on live birth rates in women over the age of 35 with a proposal for research to analyze the reasons behind the choice to elect for or aganist preimplantation genetic screening. [D] . Hufnagel, Victoria J. 2010

机译：关于植入前基因筛查与体外受精结合的影响的文献综述对35岁以上女性的活产率具有影响，并提出了一项研究建议，以分析选择选举或阿根派植入前基因筛查的背后原因。
6. Identification of mosaic and segmental aneuploidies by next-generation sequencing in preimplantation genetic screening can improve clinical outcomes compared to array-comparative genomic hybridization [O] . Hsing-Hua Lai, Tzu-Hsuan Chuang, Lin-Kin Wong, 2017

机译：与阵列比较基因组杂交相比在植入前遗传筛选中通过下一代测序鉴定镶嵌和节段非整倍性可改善临床结果
7. Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles [O] . Francesco Fiorentino, Sara Bono, Anil Biricik, 2014

机译：下一代测序技术在临床前植入遗传筛查循环中的胃囊综合排尿筛选中的应用
8. Pap Smear Challenge: Comparing Clinical Performance of a Novel Molecular Pap Based on Next-Generation Sequencing to Traditional Cervical Cancer Screening. [R] . Shen-Gunthier, J. 2018

机译：巴氏涂片挑战：比较基于下一代测序的新型分子pap在传统宫颈癌筛查中的临床表现。

Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles

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