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Risperidone: Stuttering

机译:利培酮:口吃

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Stuttering, a condition in which the normal pattern, rhythm, or timing of speech is disrupted, may be characterized by repetition and prolongation of words, phrases, and sounds, as well as hesitations or pauses that interrupt speech flow. Causes may be developmental (occurring in childhood), neurogenic (eg, head injury, stroke), or psychogenic (related to emotional trauma or stress). Because mild stuttering is often self-limiting, it is rarely treated. Patients with more severe forms often require speech therapy and counseling. Pharmacological therapy has produced inconsistent results or has been limited by side effects.It has been suggested that an antidopami-nergic effect may be beneficial in reversing stuttering problems. Risperidone, an antipsychotic approved for various psychiatric disorders, has broad neu-rotransmitter activity including antidopaminergic action and may be useful in resolving stuttering.
机译:口吃是正常语调,节奏或说话时机受到干扰的一种情况,其特征可能是单词,短语和声音的重复和延长,以及会打断语音流的犹豫或停顿。原因可能是发育性的(发生在儿童时期),神经性的(例如,头部受伤,中风)或心理性的(与情绪创伤或压力有关)。由于轻度口吃通常是自限性的,因此很少得到治疗。病情较重的患者通常需要言语治疗和咨询。药理疗法产生不一致的结果或受到副作用的限制。有人提出抗多巴胺能作用可能有助于扭转口吃问题。利培酮是一种被批准用于各种精神疾病的抗精神病药,具有广泛的神经递质活性,包括抗多巴胺能作用,可用于解决口吃。

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